Is the original data in excel, or is it a text file?
The header with the column names, in the xlsx file, some of them end with a period ( A.) whereas others end with a letter (H) do both occur in the actual data, or is this a typo?
Hi @asabhinavgreats!
I hope the attached screenshot explains the steps I tried. This fixes most of your problems. I'm sure someone will now give you three lines of python code to do the same and more, but anyway... :)
This does not address the problem with row 2 sometimes missing and also you will get empty columns at the end when you have less than the maximum number of values. That's something to keep working on.

That's a fairly (actually very) tough proposition. I think the answer from @danullen is about as good as you can get. The only thing I'd mention is that the fields A,B,C,D, etc are hard-coded in his example. If you wished to go about this dynamically (i.e. you don't know in advance) then you could use this method to generate the output schema. Instead of having _list{0}, etc you would have attribute{0}.name, attribute{0}.fme_data_type, etc.
I'd also suggest that the CAT reader (Column-Aligned Text) would be useful for reading the first few header lines; so another solution would be to basically read those lines, read the actual data with a textline reader, and basically reformat it all to create a new dataset that is simpler to carry out the actual task (ie convert it to an intermediate "format"/structure, to make the real work easier). Just a thought.