We have two FME server 2021.2.6 instances running (one Test and one Production environment) and on both environments every job/workspace fails to run with the following error.

A Python interpreter could not be loaded. Please ensure the workspace `Python Compatibility` is set to an available Python version

On one of the environments an automation runs a workspace every 5 minutes. In the logging we can see that the jobs began failing at exactly midnight 11-25-2022. The runs before midnight logged no errors, the run at midnight and all runs after that failed.

Does anybody have any suggestions what may have caused this, and how to solve this?